Objective: We previously reported how treadmill exercise can suppress cartilage degeneration. Here. we examined the changes in macrophage dynamics in knee osteoarthritis (OA) during treadmill exercise and the effect of macrophage depletion. Design: OA mouse model. https://countryscenesaddleryandpetsuppliers.shop/product-category/argentina-cow-leather-one-ear-headstall/